Organic Synthesis & Catalysis
Transition Metal Catalysis for C-H Activation/Functionalization
Medicinal Chemistry
Synthesis of New Heterocycles (Quinoline, Indole, Furan) Derivatives as Potential Therapeutic Agents
Natural Product Chemistry
Characterization of New Molecules from Western Himalayan Plants
Chemical Profiling of Medicinal Plants
Scientific Validation of Traditional Knowledge on Himalayan Plants
Cellulose Prospection from Underutilized Himalayan Bioresurce for Valuable Products
Please Visit: https://sites.google.com/site/chactivationandphytochemistry/publications
Publications
Selected Publications
Organic Synthesis, Catalysis & Medicinal Chemistry
96. Catalyst-Free Synthesis of 2-Anilinoquinolines and 3-Hydroxyquinolines via Three-Component Reaction of Quinoline N-oxides, Aryldiazonium salts and Acetonitrile.
A. K. Dhiman, D. Chandra, R. Kumar and U. Sharma*
The Journal of Organic Chemistry, 2019, DOI: 10.1021/acs.joc.9b00739. [Link]
95. Microwave-Assisted Metal-Free Rapid Synthesis of C4-Arylated Quinolines via Povarov Type Multicomponent Reaction.
D. Chandra, A. K. Dhiman, R. Kumar and U. Sharma*
European Journal of Organic Chemistry, 2019, DOI: 10.1002/ejoc.201900325. [Link]
94. Rh/O2-Catalyzed C8 Olefination of Quinoline N-oxides with Activated and Unactivated Olefins.
R. Sharma, R. Kumar and U. Sharma*
The Journal of Organic Chemistry, 2019, 84, 2786. [Link]
93. Cp*Co(III)- Alkylation of Primary and Secondary C(sp3)-H Bonds of 8-Methylquinolines with Maleimides.
R. Kumar, R. Kumar, D. Chandra and U. Sharma*
The Journal of Organic Chemistry, 2019, 84, 1542. [Link]
92. Rh(III)-Catalyzed C(8)-H Functionalization of Quinolines via Simultaneous C-C and C-O Bond Formation: Direct Synthesis of Quinoline Derivatives with Antiplasmodial Potential.
R. Sharma, R. Kumar, R. Kumar, P. Upadhyay, D. Sahal and U. Sharma*
The Journal of Organic Chemistry, 2018, 83, 12710. [Link]
91. A Catalyst and Additive-free Diastereoselective 1,3-Dipolar Cycloaddition of Quinolinium Imides with Olefins, Maleimides and Benzynes: Direct Access to Fused N,N´-Heterocycles with Promising Activity against Drug Resistant Malaria Parasite.
R. Kumar, S. Chaudhary, R. Kumar, P. Upadhyay, D. Sahal and U. Sharma*
The Journal of Organic Chemistry, 2018, 83, 11570. [Link]
90. Remote C-H Bond Activation/Transformations: A Continuous Growing Synthetic Tool; Part II.
R. Sharma, and U. Sharma*
Catalysis Reviews: Science and Engineering, 2018, 60, 497. [Link].
89. C70 Fullerene-Catalyzed Metal-Free Photocatalytic ipso-Hydroxylation of Aryl Boronic Acids: Synthesis of Phenols
I. Kumar, R. Sharma, R. Kumar, R. Kumar and U. Sharma*
Advanced Synthesis & Catalysis, 2018, 360, 2013. [Link]
88. Rhodium-Catalyzed Remote (C-8) alkylation of Quinolines with Activated and Unactivated Olefins: Mechanistic Study and Total Synthesis of EP4 Agonist
R. Sharma, I. Kumar, R. Kumar and U. Sharma*
Advanced Synthesis & Catalysis, 2017, 359, 3022. [Link]
87. Metal-free synthesis of 2-substituted-3-(2-hydroxyaryl)quinolines and 4-(2-hydroxyaryl)acridines via benzyne chemistry
A. K. Dhiman, R. Kumar, R. Kumar,* and U. Sharma*
The Journal of Organic Chemistry, 2017, 82, 12307. [Link]
86. Regioselective Metal-free C(2)-H Arylation of Quinoline N-oxides with Aryldiazonium Salts/Anilines under Ambient Conditions.
R. Kumar, R. Kumar, A. K. Dhiman and U. Sharma*
Asian Journal of Organic Chemistry, 2017, 6, 1043. [Link]
85. CuI nanoparticles as a recyclable heterogeneous catalyst for C-N bond formation reactions.
M. Kumar, V. Bhatt, O. S. Nayal, S. Sharma, V. Kumar, M. S. Thakur, N. Kumar, R. Bal,* B. Singh* and U. Sharma*
Catalysis Science & Technology, 2017, 7, 2857. [Link]
84. Synthesis of tertiary arylamines: Lewis acid-catalyzed direct reductive N- alkylation of secondary amines with ketones through an alternative pathway.
O. S. Nayal, M. S. Thakur, V. Bhatt, M. Kumar, N. Kumar, B. Singh* and U. Sharma*
Chemical Communications, 2016, 52, 9648. [Link]
83. Catalyst and Solvent-Free alkylation of Quinoline N-oxides with Olefins: Direct Access to Quinoline Substituted α–Hydroxy Carboxylic Derivatives.
R. Kumar, I. Kumar, R. Sharma and U. Sharma*
Organic & Biomolecular Chemistry, 2016, 14, 2613. [Link]
82. Rh(III)-Catalyzed Dehydrogenative Coupling of Quinoline N-Oxides with Alkenes: N-Oxide as Traceless Directing Group for Remote C-H Activation.
R. Sharma, R. Kumar, I. Kumar and U. Sharma*
European Journal of Organic Chemistry, 2015, 7519. [Link]
81. Distant C-H Activation/Functionalization: A New Horizon of Selectivity beyond Proximity.
R. Sharma, K. Thakur, R. Kumar, I. Kumar and U. Sharma*
Catalysis Reviews: Science and Engineering, 2015, 57(3), 345. [Link]
80. Orthogonal Selectivity with Cinnamic Acids in 3-Substituted Benzofuran Synthesis through C-H Olefination of Phenols.
S. Agasti, U. Sharma, T. Naveen and D. Maiti
Chemical Communications, 2015, 51, 5375.
79. Palladium-Catalyzed Annulation of Diarylamines with Olefins through C-H Activation: Direct Access to N-Arylindoles.
U. Sharma, R. Kancherla, N. Tagoti, S. Agasti amd D. Maiti
Angewandte Chemie International Edition, 2014, 53, 43.
78. Rh (III)- Catalyzed Traceless Coupling of Quinoline N-Oxides with Internal Diarylalkynes.
U. Sharma, Y. Park and S. Chang
Journal of Organic Chemistry, 2014, 79, 9899.
77. Palladium Ctalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins.
U. Sharma, N. Tagoti, A. Maji, S. Manna and D. Maiti
Angewandte Chemie International Edition, 2013, 52, 12669.
Natural Product Chemistry (Plants)
76. Pseudolycorine N-oxide, a new N-oxide from from Narcissus tazetta.
D. Katoch,* D. Kumar, Y. S. Padwad, B. Singh,* and U. Sharma*
Natural Product Research, 2019, doi.org/10.1080/14786419.2019.1574785. [Link]
75. Narciclasine-4-O-β-D-xylopyranoside, a new narciclasine glycoside from Zephyranthes minuta.
D. Katoch,* D. Kumar, Y. S. Padwad, B. Singh,* and U. Sharma*
Natural Product Research, 2019, doi.org/10.1080/14786419.2018.1527836. [Link]
74. Comprehensive metabolomics study of traditionally Important Rumex Species found in Western Himalayan region.
R. Sharma, R. Jandrotia, B. Singh, U. Sharma* and D. Kumar*
Natural Product Communications, 2018, 13, 189.
73. Comprehensive metabolic profiling of Zanthoxylum armatum and Zanthoxylum acanthopodium leaves, bark, flowers and fruits using Ultra high performance liquid chromatography.
V. Bhatt, N. Kumar, U. Sharma and B. Singh*
Separation Science Plus, 2018, 1, 311-324. [Link]
72. Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF–MS/MS.
V. Bhatt, S. Sharma, N. Kumar, U. Sharma and B. Singh
Journal of Pharmaceutical and Biomedical Analysis, 2017, 132, 46. [Link]
71. Cuspidate A, New Anti-Fungal Triterpenoid Saponin from Lepidagathis cuspidate.
R. Rattan,* B. I. Fozdar, V. Gautam, R. Sharma, D. Kumar* and U. Sharma*
Natural Product Research, 2017, 31, 773. [Link]
70. Triterpenoid Saponins from Clematis graveolens and Evaluation of their Insecticidal Activities.
R. Rattan*, S. G. E. Reddy, S. K. Dolma, B. I. Fozdar, V. Gautam, R. Sharma and U. Sharma*
Natural Product Communications, 2015, 10(9), 1525.
69. Immunomodulatory Active Compounds from Tinospora cordifolia.
U. Sharma, M. Bala, N. Kumar, R. Munshi, S. Bhalerao and B. Singh
Journal of Ethnopharmacology, 2012, 141, 918.
68. New Furostanol Saponin and Phenyl Propanoid from Roots of Asparagus racemosus.
U. Sharma, N. Kumar, and B. Singh
Natural Product Communications, 2012, 7, 995.
Full List and Details: Complete Publications Details
Book Chapters
4. Direct Arylation via C-H activation.
U. Sharma, A. Modak, S. Maity, A. Maji and D. Maiti
Thomas CoIacot eds., Introduction to New Trends in Cross-Coupling: Theory and Applications. 2014. [Link]
3. In Vitro Studies on the Antioxidant/Antigenotoxic Potential of Aqueous Fraction from Anthocephalus cadamba Bark.
M. Chandel, U. Sharma, N. Kumar, B. Singh and S. Kaur
P.R. Sudhakaran et al. (eds.), Perspectives in Cancer Prevention-Translational Cancer Research, 2013, DOI 10.1007/978-81-322-1533-25. [Link]
