Biotechnology
Senior Scientist
Microbiology and Molecular Biology
01894-233339 Ext. 422
Ph.D.

Bioprospecting genes from higher altitude microbes/plants. Extreme climatic conditions and topography of higher altitude affect both microbes and plants. In particular, we are interested in higher altitude microbes/plants functional genomics with the major focus on enzymes of industrial relevance. Currently, we are targeting therapeutic proteins and industrially relevant enzymes from higher altitude microbes. Our strategy includes multi-dimensional approaches such as whole genome sequencing, proteomics, genetics, and bioinformatics to develop a bioprocess for the industrial use.

 

Selected “Assistant Director” State Forensic Science Laboratory, Junga, Shimla, Himachal Pradesh through Public Service Commission (open competition) in the year 2009.

Awarded “Distinguished Postdoctoral Fellowship” by Academia Sinica, Taiwan for year 2009-2011.

Awarded “Young Scientist International Travelling Fellowship” by Japan Society for Promotion of Science (JSPS, Japan) for participation in the JSPS-DST Asian Academic Seminar 2008 held at Jawarharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.

Awarded “International Travelling Fellowship” by Institute of Molecular Biology, Academia Sinica, Taiwan for the year 2007.

Selected as Scientist Gr. IV(1) at CSIR-NEIST, Jorhat, India (2005).

1.     

Latest ten papers

2020

1. Kumari M, Kumar R, Singh D, Bhatt S and Gupta M (2020). Physiological and genomic characterization of an exopolysaccharide-producing Weissella cibaria CH2 from cheese of the western Himalayas. Food Bioscience, accepted article (IF: 3.220).

2. Singh D, Murashko O N, and Lin-Chao S (2020). Post-transcriptional regulation of tnaA by protein-RNA interaction mediated by ribosomal protein L4 in Escherichia coli. J Bacteriol (IF: 3.234)

3. Kashyap P, Kumar S and Singh D (2020). Performance of antifreeze protein HrCHI4 from Hippophae rhamnoides in improving the structure and freshness of green beans upon cryopreservation. Food Chemistry (IF: 5.339).

 2019

4. Kumar V, Kumar  S, and Singh D (2019). Microbial polyhydroxyalkanoates from extreme niches: bioprospection status, opportunities and challenges. Available online 15 November https://doi.org/10.1016/j.ijbiomac.2019.09.253 Int J Biol Macromol (IF: 4.784)

5. Kumar V, Kumar  S, Darnal S, Patial V, Singh A, Thakur V, Kumar S, and Singh D (2019). Optimized chromogenic dyes-based identification and quantitative evaluation of bacterial L-asparaginase with low/no glutaminase activity bioprospected from pristine niches in Indian trans-Himalaya. 3 Biotech, online June 20, 2019.  https ://doi.org/10.1007/s1320 5-019-1810-9. (IF: 1.36)

6. Kumar V, Thakur V, Ambika, Kumar V, Kumar R, and Singh D  (2019). Genomic insights revealed  physiological diversity and industrial potential for Glaciimonas sp. PCH181 isolated from Satrundi glacier in Pangi-Chamba Himalaya. Genomics. https://doi.org/10.1016/j.ygeno.2019.04.016, online April 22 2019.   (IF: 3.160)

2018

7. Mahajan R, Verma S, Kushwaha M, Singh D, Akhter Y, Chatterjee S (2018). Biodegradation of di-n-butyl phthalate by psychrotolerant Sphingobium yanoikuyae strain P4 and protein structural analysis of carboxylesterase involved in the pathway. Int J Biol Macromol. (IF: 4.784).

8. Sharma S, Patial V, Singh D, Sharma U, Kumar D (2018). Antimicrobial homoisoflavonoids from the rhizomes of Polygonatum verticillatum. Chemistry & Biodiversity. Published online Oct 18, 2018. doi: 10.1002/cbdv.201800430 (IF: 1.449)

9. Kumar V, Thakur V, Ambika,  Kumar S, Singh D (2018).  Bioplastic reservoir of diverse bacterial communities revealed along altitude gradient of Pangi-Chamba trans-Himalayan region. FEMS Microbiology Letters doi/10.1093/femsle/fny144/5037922 (IF: 1.994).

10. Thakur V, Kumar V, Kumar S, Singh D (2018). Diverse culturable bacterial communities with        cellulolytic potential revealed from pristine habitat in Indian trans-Himalaya. Canadian Journal of Microbiology https://doi.org/10.1139/cjm-2017-0754. (IF: 1.550).

 

 

Post-doctoral Fellow:  Dr. Vijay Kumar

PhD Fellows: Sanyukta Darnal, Ambika, Subhash Kumar, Vikas Thakur, 

                      Vijeta Patial, and Deepika Naag

Women Scientist Fellow: Ritu Sharma

Project Fellows: Suresh Kumar, Anchal

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