Validation of natural products, nutraceuticals and drug molecules for their therapeutic potential in liver and kidney disease models.

Preclinical safety/toxicity studies

IAVP-Dr B.L. Purohit Memorial Best Toxico-Pathologist Award-2024 

Selected to attend “Young Scientist Camp-2023” at Seoul National University, South Korea by AFLAS 

IAVP-Prof. S. Ramachandran Memorial Award 2022

Best Poster Award, SFEC-2022, International Congress of Society of Ethnopharmacology

Best Poster Award, Indian Academy of Biomedical Sciences (2019)

Certificate of Appreciation in Dr P.D. Sethi Memorial Annual National Awards -2017

ASRB-NET qualified (Veterinary Pathology)

Awarded certificate of honour for BVSc & AH 

Awarded merit scholarship in BVSc & AH and MVSc

Awarded Certificate of Merit under the National Scholarships Scheme in Matriculation 

Swati Katoch, Jatin, Vishal Acharya, Vikram Patial* (2026). Picrosides I and II Ameliorate Steatosis by Modulating Lipogenesis, Mitochondrial Biogenesis, and Autophagy in Hepatic Cells.  Cell Biology international, https://doi.org/10.1002/cbin.70170.

Shagun Sanjivv Dogra, Vikram Patial* (2026).Iridoids in liver diseases: Mechanistic insights and molecular mechanism. Journal of Integrative Medicine. https://doi.org/10.1016/j.joim.2026.01.008.

Vinesh Sharma, Raman Kumar, Robin Joshi, Vidyashankar Srivatsan, Vikram Patial* (2025). Malnutrition induces steatohepatitis by impairing hepatic lipid metabolism, mitochondrial function and the gut-liver axis. Journal of Physiology and Biochemistry. doi: 10.1007/s13105-025-01125-3.

Swati Katoch, Jyoti Chhimwal, Damanpreet Singh, Dinesh Kumar, Vikram Patial* (2025). Picrosides-rich fraction from Picrorhiza kurroa attenuates steatohepatitis in zebrafish and mice by modulating lipid metabolism and inflammation. Phytomedicine. 137: 156368. https://doi.org/10.1016/j.phymed.2025.156368.

Vinesh Sharma, Vikram Patial* (2024). Insights into the molecular mechanisms of malnutrition-associated steatohepatitis: A review. Liver International. 1-18. doi: 10.1111/liv.15932.

Pragya Choubey, Vinesh Sharma, Robin Joshi, Ashwani Upadhyaya, Dinesh Kumar, Vikram Patial* (2024). Hydroethanolic extract of Gentiana kurroo Royle rhizome ameliorates ethanol-induced liver injury by reducing oxidative stress, inflammation and fibrogenesis in rats. Journal of Ethnopharmacology. 117866. https://doi.org/10.1016/j.jep.2024.117866.

Vikram Patial*, Swati Katoch Jyoti Chhimwal, Garima Dadhich, Vinesh Sharma, Ajay Rana, Robin Joshi, Yogendra Padwad* (2023). Catechins prevent obesity-induced kidney damage by modulating PPARγ/CD36 pathway and gut-kidney axis in rats. Life Sciences. 121437. https://doi.org/10.1016/j.lfs.2023.121437.

Raman Kumar, Vinesh Kumar, Sampa Das, Vikram Patial*, Vidyashankar Srivatsan* (2023). Arthrospira platensis (Spirulina) fortified functional foods ameliorates iron and protein malnutrition by improving growth, modulating oxidative stress and gut microbiota in rats. Food & Function (RSC). https://doi.org/10.1039/D2FO02226E.

Jyoti Chhimwal, Abhishek Goel, Mahesh Sukapaka, Vikram Patial*, Yogendra Padwad* (2022). Phloretin mitigates oxidative injury, inflammation and fibrogenic responses via restoration of autophagic flux in in-vitro and pre-clinical models of NAFLD. Journal of Nutritional Biochemistry, 109062.https://doi.org/10.1016/j.jnutbio.2022.109062.

Desh Raj, Vinesh Sharma, Ashwani Upadhyaya, Neeraj Kumar, Robin Joshi, Vishal Acharya, Dinesh Kumar, Vikram Patial* (2022). Swertia purpurascens Wall ethanolic extract mitigates hepatic fibrosis and restores hepatic hepcidin levels via inhibition of TGFβ/SMAD/NFκB signaling in rats. Journal of Ethnopharmacology. https://doi.org/10.1016/j.jep.2021.114741.

Vikram Patial*, Swati Katoch, Jyoti Chhimwal, Prithvi Pal Singh, Patil Shivprasad Suresh, Yogendra Padwad* (2021). Tinospora cordifolia activates PPARγ pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine, https://doi.org/10.1016/j.phymed.2021.153663.

Swati Katoch, Vikram Patial* (2020). Zebrafish: An emerging model system to study liver diseases and related drug discovery. Journal of Applied Toxicology, 1-19 doi:10.1002/jat.4031

Supriya Sharma⁠, ⁠Pallavi Sharma⁠, Pankaj Kulurkar⁠, Damanpreet Singh⁠⁠, Dinesh Kumar*⁠, Vikram Patial* (2017). Iridoid glycosides fraction from Picrorhiza kurroa attenuates cyclophosphamide-induced renal toxicity and peripheral neuropathy via PPAR-γ mediated inhibition of inflammation and apoptosis. Phytomedicine, 36: 108-117.

PhD Scholars:

Vinesh Sharma- ICMR SRF

Swati Katoch- PA

Prakriti Sharma- CSIR JRF

Vivek Kumar- CSIR GPAT

Shagun Dogra- ICMR SRF

Sahiba Chahal- CSIR JRF

Sheetal Bali - UGC JRF