Food and Nutraceuticals
Scientist
Animal Pathology, Toxicopathology
01894-233339 Ext. 452
B.V.Sc. & A.H., M.V.Sc. (Veterinary Pathology)

Preclinical safety/toxicity studies 

Scientific validation of natural products, nutraceuticals and drug molecules for their therapeutic potential in liver and kidney disease models.

ICAR-NET qualified in Veterinary Pathology

Awarded certificate of honour for BVSc & AH and MVSc

Awarded merit scholarship in BVSc & AH and MVSc

Awarded National Merit Scholarship in Matriculation

Supriya Sharma, Mehak, Jyoti Chhimwal, Vikram Patial*, Ugir Hossain Sk (2019). Dendrimer-conjugated podophyllotoxin suppresses DENA-induced HCC progression by modulation of inflammatory and fibrogenic factors. Toxicology Research. 8, 560–567.

Arindam Ghosh Mazumder, Vikram Patial, Damanpreet Singh (2019). Mycophenolate mofetil contributes to downregulation of the hippocampal interleukin type 2 and 1β mediated PI3K/AKT/mTOR pathway hyperactivation and attenuates neurobehavioral comorbidities in a rat model of temporal lobe epilepsyBrain, Behavior, and Immunity. 75, 84–93.

Supriya SharmaPallavi Sharma, Pankaj Kulurkar, Damanpreet Singh⁠⁠, Dinesh Kumar*Vikram Patial* (2017). Iridoid glycosides fraction from Picrorhiza kurroa attenuates cyclophosphamide-induced renal toxicity and peripheral neuropathy via PPAR-γ mediated inhibition of inflammation and apoptosis. Phytomedicine, 36: 108-117.

Shiv Kumar, Vikram Patial, Sourabh Soni, Supriya Sharma, Kunal Pratap, Dinesh Kumar and Yogendra Padwad (2017). Picrorhiza kurroa enhances β-cell mass proliferation and insulin secretion in streptozotocin evoked β-cell damage in rats. Frontiers in Pharmacology. doi: 10.3389/fphar.2017.00537

Supriya Sharma, Shalika Rana, Vikram Patial*, Mahesh Gupta, Shashi Bhushan Yogendra S Padwad (2016). Antioxidant and hepatoprotective effect of polyphenols from apple pomace extract via apoptosis inhibition and Nrf2 activation in mice. Human and Experimental Toxicology, 35(12): 1264-75.

Shanka Walia, Supriya Sharma, Pankaj Markand Kulurkar, Vikram Patial*, Amitabha Acharya* (2016). A bimodal molecular imaging probe based on chitosan encapsulated magneto-fluorescent nanocomposite offers biocompatibility, visualization of specific cancer cells in vitro and lung tissues in vivo. International Journal of Pharmaceutics, 498:110-118.

Vikram Patial*, Mahesh S, Supriya Sharma, Kunal Pratap, Damanpreet Singh, Yogendra S. Padwad (2015). Synergistic effect of curcumin and piperine in suppression of DENA-induced hepatocellular carcinoma in rats. Environmental Toxicology and Pharmacology. 40: 445-452. 

Dr. Pankaj Kulurkar- Senior Technical Officer

Project Assistants: Swati Katoch , Vinesh Sharma, Anchal, Garima Dadhich

 

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